PHAGE DISPLAY LIBRARY

phage display library: translation

Phage library in which the insert is expressed as a translational fusion with a phage coat protein. This makes it particularly easy to screen with antibodies. Widely used to identify epitopes recognized by some particular antibody; commercial phage display libraries randomly encoding all possible 6 or 7 residue peptides can be screened with the antibody, and the inserts of bound phage sequenced to build up a picture of the binding profile of the antibody.