FOREIGN BODY GIANT CELL

foreign body giant cell: translation

Syncytium formed by the fusion of macrophages in response to an indigestible particle too large to be phagocytosed (eg. talc, silica or asbestos fibres). There may be as many as 100 nuclei randomly distributed: similar cells but with the nuclei more peripherally located (Langhans cells) are found at the centre of tuberculous lesions.

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